HLA class I-restricted cytotoxic T-cell epitopes of the respiratory syncytial virus fusion protein.
نویسندگان
چکیده
Virus-specific cytotoxic T lymphocytes (CTL) play a major role in the clearance of respiratory syncytial virus (RSV) infection. We have generated cytotoxic T-cell clones (TCC) from two infants who had just recovered from severe RSV infection. These TCC were functionally characterized and used to identify HLA class I (B57 and C12)-restricted CTL epitopes of RSV.
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عنوان ژورنال:
- Journal of virology
دوره 74 21 شماره
صفحات -
تاریخ انتشار 2000